Human Thyroid Peroxidase (TPO) Protein
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Catalogue No: abx073668
Price:
US$261.00
(Size: 5 µg)
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Datasheet SDS
TPO or thyroperoxidase (TPO) is an enzyme expressed mainly in the thyroid where it is secreted into colloid. TPO oxidizes iodide ions to form iodine atoms for addition onto tyrosine residues on thyroglobulin for the production of thyroxine (T4) or triiodothyronine (T3), the thyroid hormones. In humans, thyroperoxidase is encoded by the TPO gene. The recombinant Human TPO protein is produced in an insect (SF9). It is a glycosylated polypeptide chain with a wide application in molecular research.
Research Articles on Thyroid Peroxidase (TPO)
| Target | Thyroid Peroxidase (TPO) |
| Research Area | Enzymes and Kinases, Endocrinology, Hormone Metabolism |
| Origin | Human |
| Expression | Recombinant |
| Tested Applications | SDS-PAGE |
| Host | Insect |
| Recommended dilutions | ELISA (coating): 0.15 - 0.375 µg/ml (depending on the type of ELISA plate and coating buffer). Suitable for biotinylation and iodination. Optimal dilutions/concentrations should be determined by the end user. |
| Activity | Not tested |
| Purity | > 95% (SDS-PAGE) |
| Purification | Purified by proprietary chromatographic techniques. |
| Storage | Store at -20°C for long term storage or at 4°C for up to 1 month. For long term storage, it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P07202 (UniProt, ExPASy) |
| Molecular Weight | 92.9 kDa (excluding glycosylation) 101 kDa (including glycosylation) |
| Sequence Fragment | 834 AA. |
| Tag | 6 His tag |
| Buffer | 16 mM HEPES, pH 7.6, 160 mM NaCl, 0.08 mM Kl and 20% glycerol. |
| Concentration | 0.6 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |