Tumor Necrosis Factor Receptor Type 1-Associated DEATH Domain Protein (TRADD) Antibody

TRADD Antibody is a Rabbit Polyclonal antibody against TRADD. The protein encoded by this gene is a death domain containing adaptor molecule that interacts with TNFRSF1A/TNFR1 and mediates programmed cell death signaling and NF-kappaB activation. This protein binds adaptor protein TRAF2, reduces the recruitment of inhibitor-of-apoptosis proteins (IAPs) by TRAF2, and thus suppresses TRAF2 mediated apoptosis. This protein can also interact with receptor TNFRSF6/FAS and adaptor protein FADD/MORT1, and is involved in the Fas-induced cell death pathway.

Target	Tumor Necrosis Factor Receptor Type 1-Associated DEATH Domain Protein (TRADD)
Clonality	Polyclonal
Reactivity	Human, Mouse
Tested Applications	WB
Host	Rabbit
Recommended dilutions	WB: 1/1000 - 1/5000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 199-312 of human TRADD.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q15628 (UniProt, ExPASy)
UniProt Secondary AC	B2RDS3, B3KQZ9, Q52NZ1
UniProt Entry Name	TRADD_HUMAN
Gene Symbol	TRADD
GeneID	8717
NCBI Accession	NP_003780.1
KEGG	hsa:8717
String	9606.ENSP00000341268
Molecular Weight	Calculated MW: 34 kDa Observed MW: 36 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Tumor Necrosis Factor Receptor Type 1-Associated DEATH Domain Protein (TRADD)

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