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Tumor Necrosis Factor Receptor Type 1-Associated DEATH Domain Protein (TRADD) Antibody
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Catalogue No: abx001059
Price:
£120.00
(Size: 20 µl)
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TRADD Antibody is a Rabbit Polyclonal antibody against TRADD. The protein encoded by this gene is a death domain containing adaptor molecule that interacts with TNFRSF1A/TNFR1 and mediates programmed cell death signaling and NF-kappaB activation. This protein binds adaptor protein TRAF2, reduces the recruitment of inhibitor-of-apoptosis proteins (IAPs) by TRAF2, and thus suppresses TRAF2 mediated apoptosis. This protein can also interact with receptor TNFRSF6/FAS and adaptor protein FADD/MORT1, and is involved in the Fas-induced cell death pathway.
Research Articles on TRADD
| Target | TRADD |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | WB, IHC, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000, IHC: 1/50 - 1/100, IF/ICC: 1/50 - 1/100. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant protein of human TRADD. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q15628 (UniProt, ExPASy) |
| UniProt Secondary AC | B2RDS3, B3KQZ9, Q52NZ1 |
| UniProt Entry Name | TRADD_HUMAN |
| Gene Symbol | TRADD |
| GeneID | 8717 |
| KEGG | hsa:8717 |
| String | 9606.ENSP00000341268 |
| Molecular Weight | Calculated MW: 34 kDa Observed MW: 36 kDa |
| Buffer | PBS, pH 7.3, 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.5 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |
