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TNF Receptor-Associated Factor 3 (TRAF3) Antibody
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Catalogue No: abx002224
Price:
£120.00
(Size: 20 µl)
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TRAF3 Antibody is a Rabbit Polyclonal antibody against TRAF3. The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from, members of the TNF receptor (TNFR) superfamily. This protein participates in the signal transduction of CD40, a TNFR family member important for the activation of the immune response. This protein is found to be a critical component of the lymphotoxin-beta receptor (LTbetaR) signaling complex, which induces NF-kappaB activation and cell death initiated by LTbeta ligation. Epstein-Barr virus encoded latent infection membrane protein-1 (LMP1) can interact with this and several other members of the TRAF family, which may be essential for the oncogenic effects of LMP1. Several alternatively spliced transcript variants encoding three distinct isoforms have been reported.
Research Articles on TRAF3
| Target | TRAF3 |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB, IHC, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/200 - 1/1000, IHC: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | A synthetic peptide of human TNF receptor-associated factor 3. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q13114 (UniProt, ExPASy) |
| UniProt Secondary AC | B7Z8C4, Q12990, Q13076, Q13947, Q6AZX1, Q9UNL1 |
| UniProt Entry Name | TRAF3_HUMAN |
| Gene Symbol | TRAF3 |
| GeneID | 7187 |
| KEGG | hsa:7187 |
| String | 9606.ENSP00000454207 |
| Molecular Weight | Calculated MW: 55 kDa, 64 kDa Observed MW: 70 kDa |
| Buffer | PBS, pH 7.3, 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.5 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |
