TNF Receptor-Associated Factor 3 (TRAF3) Antibody

Catalogue No: abx002224
Price: £120.00
(Size: 20 µl)
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TRAF3 Antibody is a Rabbit Polyclonal antibody against TRAF3. The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from, members of the TNF receptor (TNFR) superfamily. This protein participates in the signal transduction of CD40, a TNFR family member important for the activation of the immune response. This protein is found to be a critical component of the lymphotoxin-beta receptor (LTbetaR) signaling complex, which induces NF-kappaB activation and cell death initiated by LTbeta ligation. Epstein-Barr virus encoded latent infection membrane protein-1 (LMP1) can interact with this and several other members of the TRAF family, which may be essential for the oncogenic effects of LMP1. Several alternatively spliced transcript variants encoding three distinct isoforms have been reported.

Target TRAF3
Clonality Polyclonal
Reactivity Human, Mouse
Tested Applications WB, IF/ICC
Host Rabbit
Recommended dilutions WB: 1/200 - 1/1000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen A synthetic peptide of human TNF receptor-associated factor 3.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q13114 (UniProt, ExPASy)
UniProt Secondary AC B7Z8C4, Q12990, Q13076, Q13947, Q6AZX1, Q9UNL1
UniProt Entry Name TRAF3_HUMAN
Gene Symbol TRAF3
GeneID 7187
KEGG hsa:7187
String 9606.ENSP00000454207
Molecular Weight Calculated MW: 55 kDa, 64 kDa
Observed MW: 70 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on TNF Receptor-Associated Factor 3 (TRAF3) Antibody

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