Transcription Factor SOX-2 (SOX2) Antibody

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Catalogue No: abx240016
Price: US$406.00
(Size: 100 µg)

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Transcription Factor SOX-2 (SOX2) Antibody Transcription Factor SOX-2 (SOX2) Antibody

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Datasheet SDS
Transcription Factor SOX-2 (SOX2) Antibody is a Mouse Monoclonal antibody for the detection of SOX2.

Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206 (By similarity). Critical for early embryogenesis and for embryonic stem cell pluripotency. May function as a switch in neuronal development. Downstream SRRT target that mediates the promotion of neural stem cell self-renewal (By similarity). Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation (By similarity).

Target Transcription Factor SOX-2 (SOX2)
Clonality Monoclonal
Reactivity Human, Mouse
Tested Applications ELISA, WB, IHC
Host Mouse
Recommended dilutions WB: 1/500 - 1/2000, IHC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen SRY(sex determining region Y)-box 2
Isotype IgG1
Form Liquid
Purity ≥ 95% (SDS-PAGE)
Purification Purified by Protein A and Protein G affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Validity 12 months.
UniProt Primary AC P48431 (UniProt, ExPASy)
UniProt Secondary AC Q14537
UniProt Entry Name SOX2_HUMAN
Gene Symbol SOX2
GeneID 6657
OMIM 184429
HGNC 11195
KEGG hsa:6657
Ensembl ENSG00000181449
String 9606.ENSP00000323588
Molecular Weight Observed MW: 34 kDa
Buffer PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol.
Concentration 2 mg/ml
Availability Shipped within 5-12 working days.
Note THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
Research Articles on Transcription Factor SOX-2 (SOX2)


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