Transient Receptor Potential Cation Channel Subfamily V Member 1 (TRPV1) Antibody
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Catalogue No: abx240190
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US$420.50
(Size: 100 µg)
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Datasheet SDS
Transient Receptor Potential Cation Channel Subfamily V Member 1 (TRPV1) Antibody is a Rabbit Polyclonal antibody for the detection of TRPV1. Capsaicin, the main pungent ingredient in hot chili peppers, elicits a sensation of burning pain by selectively activating sensory neurons that convey information about noxious stimuli to the central nervous system. The protein encoded by this gene is a receptor for capsaicin and is a non-selective cation channel that is structurally related to members of the TRP family of ion channels. This receptor is also activated by increases in temperature in the noxious range, suggesting that it functions as a transducer of painful thermal stimuli in vivo. Four transcript variants encoding the same protein, but with different 5' UTR sequence, have been described for this gene.
Research Articles on Transient Receptor Potential Cation Channel Subfamily V Member 1 (TRPV1)
| Target | Transient Receptor Potential Cation Channel Subfamily V Member 1 (TRPV1) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/200 - 1/2000, IHC: 1/20 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | centromere protein H |
| Isotype | IgG |
| Form | Liquid |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by immunogen affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | Q8NER1 (UniProt, ExPASy) |
| UniProt Secondary AC | A2RUA9, Q3LU47, Q9H0G9, Q9H303, Q9H304, Q9NQ74, Q9NY22 |
| UniProt Entry Name | TRPV1_HUMAN |
| Gene Symbol | TRPV1 |
| GeneID | 7442 |
| NCBI Accession | NP_061197.4 |
| KEGG | hsa:7442 |
| String | 9606.ENSP00000461007 |
| Molecular Weight | Observed MW: 110 kDa |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Concentration | 2 mg/ml |
| Availability | Shipped within 5-12 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |