Transient Receptor Potential Cation Channel Subfamily V Member 1 (TRPV1) Antibody

Transient Receptor Potential Cation Channel Subfamily V Member 1 (TRPV1) Antibody is a Rabbit Polyclonal antibody for the detection of TRPV1.

Capsaicin, the main pungent ingredient in hot chili peppers, elicits a sensation of burning pain by selectively activating sensory neurons that convey information about noxious stimuli to the central nervous system. The protein encoded by this gene is a receptor for capsaicin and is a non-selective cation channel that is structurally related to members of the TRP family of ion channels. This receptor is also activated by increases in temperature in the noxious range, suggesting that it functions as a transducer of painful thermal stimuli in vivo. Four transcript variants encoding the same protein, but with different 5' UTR sequence, have been described for this gene.

Target	Transient Receptor Potential Cation Channel Subfamily V Member 1 (TRPV1)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	ELISA, WB, IHC
Host	Rabbit
Recommended dilutions	WB: 1/200 - 1/2000, IHC: 1/20 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	centromere protein H
Isotype	IgG
Form	Liquid
Purity	≥ 95% (SDS-PAGE)
Purification	Purified by immunogen affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Validity	12 months.
UniProt Primary AC	Q8NER1 (UniProt, ExPASy)
UniProt Secondary AC	A2RUA9, Q3LU47, Q9H0G9, Q9H303, Q9H304, Q9NQ74, Q9NY22
UniProt Entry Name	TRPV1_HUMAN
Gene Symbol	TRPV1
GeneID	7442
NCBI Accession	NP_061197.4
KEGG	hsa:7442
String	9606.ENSP00000461007
Molecular Weight	Observed MW: 110 kDa
Buffer	PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol.
Concentration	2 mg/ml
Availability	Shipped within 5-12 working days.
Note	This product is for research use only.

Research Articles on Transient Receptor Potential Cation Channel Subfamily V Member 1 (TRPV1)

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