Triggering Receptor Expressed On Myeloid Cells 1 (TREM1) Antibody

Monocyte/macrophage and neutrophil-mediated inflammatory responses can be stimulated through a variety of receptors, including G protein-linked 7-transmembrane receptors (e.g., FPR1; MIM 136537), Fc receptors (see MIM 146790), CD14 (MIM 158120) and Toll-like receptors (e.g., TLR4; MIM 603030), and cytokine receptors (e.g., IFNGR1; MIM 107470). Engagement of these receptors can also prime myeloid cells to respond to other stimuli. Myeloid cells express receptors belonging to the Ig superfamily, such as TREM1, or to the C-type lectin superfamily. Depending on their transmembrane and cytoplasmic sequence structure, these receptors have either activating (e.g., KIR2DS1; MIM 604952) or inhibitory functions (e.g., KIR2DL1; MIM 604936).

Target	Triggering Receptor Expressed On Myeloid Cells 1 (TREM1)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB
Host	Rabbit
Recommended dilutions	WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 162-191 amino acids from the C-terminal region of human TREM1.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q9NP99 (UniProt, ExPASy)
UniProt Secondary AC	B4DWG2, K7EJW1, Q53FL8, Q5T2C9, Q86YU1
UniProt Entry Name	TREM1_HUMAN
Gene Symbol	TREM1
String	9606.ENSP00000244709
Molecular Weight	Calculated MW: 26.4 kDa
Buffer	PBS containing 0.09% sodium azide.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Triggering Receptor Expressed On Myeloid Cells 1 (TREM1)

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