TRIM21 Antibody is a Rabbit Polyclonal antibody against TRIM21. TRIM21 has multiple N-terminal zinc finger motifs(has E3 ligase activity), a central leucine zipper, and a potential N-glycosylation site. TRIM3 is a E3 ubiquitin-protein ligase. It can form a ubiquitin ligase complex with E2 UBE2D2, which function not only for the uniquitination of USP4 and IKBKB but also for its self-ubiquitination. It has a role in the regulation of the cell cycle progression and could enhance the decapping activity of DCP2. It can exist in all mammalian cells as a ribonucleoprotein particle, which composed of a single polypeptide and 1 of 4 small RNA molecules.
| Target |
TRIM21 |
| Clonality |
Polyclonal |
| Reactivity |
Human |
| Tested Applications |
WB, IF/ICC |
| Host |
Rabbit |
| Recommended dilutions |
WB: 1/500 - 1/2000, IF/ICC: 1/10 - 1/100. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation |
Unconjugated |
| Immunogen |
Recombinant protein of human TRIM21. |
| Isotype |
IgG |
| Form |
Liquid |
| Purification |
Affinity purified. |
| Storage |
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC |
P19474 (UniProt,
ExPASy)
|
| UniProt Secondary AC |
Q5XPV5, Q96RF8 |
| UniProt Entry Name |
RO52_HUMAN |
| Gene Symbol |
TRIM21 |
| GeneID |
6737
|
| KEGG |
hsa:6737
|
| String |
9606.ENSP00000254436
|
| Molecular Weight |
Calculated MW: 45 kDa, 54 kDa
Observed MW: 52 kDa |
| Buffer |
PBS, pH 7.3, 0.02% sodium azide, 50% glycerol. |
| Concentration |
> 1 mg/ml |
| Availability |
Shipped within 5-10 working days. |
| Note |
This product is for research use only. |
Research Articles on Tripartite Motif Containing 21 (TRIM21) Antibody
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