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E3 Ubiquitin-Protein Ligase TRIM21 (TRIM21) Antibody
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Catalogue No: abx001596
Price:
US$203.00
(Size: 20 µl)
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E3 Ubiquitin-Protein Ligase TRIM21 (TRIM21) Antibody is a Rabbit Polyclonal antibody against E3 Ubiquitin-Protein Ligase TRIM21 (TRIM21). E3 Ubiquitin-Protein Ligase TRIM21 (TRIM21) has multiple N-terminal zinc finger motifs(has E3 ligase activity), a central leucine zipper, and a potential N-glycosylation site. TRIM3 is a E3 ubiquitin-protein ligase. It can form a ubiquitin ligase complex with E2 UBE2D2, which function not only for the uniquitination of USP4 and IKBKB but also for its self-ubiquitination. It has a role in the regulation of the cell cycle progression and could enhance the decapping activity of DCP2. It can exist in all mammalian cells as a ribonucleoprotein particle, which composed of a single polypeptide and 1 of 4 small RNA molecules.
Research Articles on E3 Ubiquitin-Protein Ligase TRIM21 (TRIM21)
| Target | E3 Ubiquitin-Protein Ligase TRIM21 (TRIM21) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB, IHC, IF/ICC, IP |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/1000, IHC-P: 1/50 - 1/200, IF/ICC: 1/50 - 1/200, IP: 0.5-4 µg/200-400 µg whole cell extracts. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 86-334 of human TRIM21/SS-A. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P19474 (UniProt, ExPASy) |
| UniProt Secondary AC | Q5XPV5, Q96RF8 |
| UniProt Entry Name | RO52_HUMAN |
| Gene Symbol | TRIM21 |
| GeneID | 6737 |
| NCBI Accession | NP_003132.2 |
| KEGG | hsa:6737 |
| String | 9606.ENSP00000254436 |
| Molecular Weight | Calculated MW: 54 kDa Observed MW: 50 kDa |
| Buffer | PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |
