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Tripartite Motif Containing 21 (TRIM21) Antibody
Catalogue No: abx001596
Price:
£120.00
(Size: 20 µl)
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TRIM21 Antibody is a Rabbit Polyclonal antibody against TRIM21. TRIM21 has multiple N-terminal zinc finger motifs(has E3 ligase activity), a central leucine zipper, and a potential N-glycosylation site. TRIM3 is a E3 ubiquitin-protein ligase. It can form a ubiquitin ligase complex with E2 UBE2D2, which function not only for the uniquitination of USP4 and IKBKB but also for its self-ubiquitination. It has a role in the regulation of the cell cycle progression and could enhance the decapping activity of DCP2. It can exist in all mammalian cells as a ribonucleoprotein particle, which composed of a single polypeptide and 1 of 4 small RNA molecules.
Research Articles on TRIM21
| Target | TRIM21 |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB, IHC, IF/ICC, IP |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000, IHC: 1/10 - 1/100, IF/ICC: 1/10 - 1/100, IP: 1/10 - 1/100. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant protein of human TRIM21. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P19474 (UniProt, ExPASy) |
| UniProt Secondary AC | Q5XPV5, Q96RF8 |
| UniProt Entry Name | RO52_HUMAN |
| Gene Symbol | TRIM21 |
| GeneID | 6737 |
| KEGG | hsa:6737 |
| String | 9606.ENSP00000254436 |
| Molecular Weight | Calculated MW: 45 kDa, 54 kDa Observed MW: 52 kDa |
| Buffer | PBS, pH 7.3, 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.5 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |
