Tripartite Motif Containing 21 (TRIM21) Antibody

Catalogue No: abx001596
Price: £120.00
(Size: 20 µl)
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TRIM21 Antibody is a Rabbit Polyclonal antibody against TRIM21. TRIM21 has multiple N-terminal zinc finger motifs(has E3 ligase activity), a central leucine zipper, and a potential N-glycosylation site. TRIM3 is a E3 ubiquitin-protein ligase. It can form a ubiquitin ligase complex with E2 UBE2D2, which function not only for the uniquitination of USP4 and IKBKB but also for its self-ubiquitination. It has a role in the regulation of the cell cycle progression and could enhance the decapping activity of DCP2. It can exist in all mammalian cells as a ribonucleoprotein particle, which composed of a single polypeptide and 1 of 4 small RNA molecules.

Target TRIM21
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB, IHC, IF/ICC, IP
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IHC: 1/10 - 1/100, IF/ICC: 1/10 - 1/100, IP: 1/10 - 1/100. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human TRIM21.
Isotype IgG
Form Liquid
Purification Purified by affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P19474 (UniProt, ExPASy)
UniProt Secondary AC Q5XPV5, Q96RF8
UniProt Entry Name RO52_HUMAN
Gene Symbol TRIM21
GeneID 6737
KEGG hsa:6737
String 9606.ENSP00000254436
Molecular Weight Calculated MW: 45 kDa, 54 kDa
Observed MW: 52 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 0.5 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on TRIM21

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