Tripartite Motif Containing 22 (TRIM22) Antibody

The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to the cytoplasm and its expression is induced by interferon. The protein down-regulates transcription from the HIV-1 LTR promoter region, suggesting that function of this protein may be to mediate interferon's antiviral effects.

Target	Tripartite Motif Containing 22 (TRIM22)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB
Host	Rabbit
Recommended dilutions	WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 67-96 amino acids from the N-terminal region of human TRIM22.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q8IYM9 (UniProt, ExPASy)
UniProt Secondary AC	Q05CQ0, Q15521
UniProt Entry Name	TRI22_HUMAN
Gene Symbol	TRIM22
KEGG	hsa:10346
String	9606.ENSP00000369299
Molecular Weight	Calculated MW: 56.9 kDa
Buffer	PBS containing 0.09% sodium azide.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Tripartite Motif Containing 22 (TRIM22)

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