Troponin I, Cardiac Muscle (TNNI3) Antibody

Troponin I, Cardiac Muscle (TNNI3) Antibody is a Mouse Monoclonal antibody for the detection of Cardiac Troponin I .

Troponin I (TnI) is the inhibitory subunit of troponin, the structural protein involved in the regulation of striated muscle contraction. Cardiac Troponin I (cTnI) is produced by cardiac muscle. cTnI has been considered as one of the most specific and sensitive markers of myocardial damage like acute myocardial infarction (AMI) for decades. Detection of cTnI in serum is widely accepted as a diagnostic tool in acute coronary syndromes.

Target	Troponin I, Cardiac Muscle (TNNI3)
Clonality	Monoclonal
Reactivity	Human, Mouse, Rat
Tested Applications	ELISA, WB, IHC, IF/ICC
Host	Mouse
Recommended dilutions	WB: 1/5000 - 1/50000, IHC: 1/50 - 1/500, IF/ICC: 1/50 - 1/500. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	troponin I type 3 (cardiac)
Isotype	IgG1
Form	Liquid
Purity	≥ 95% (SDS-PAGE)
Purification	Purified by Protein A and Protein G affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Validity	12 months.
UniProt Primary AC	P19429 (UniProt, ExPASy)
UniProt Entry Name	TNNI3_HUMAN
Gene Symbol	TNNI3
GeneID	7137
OMIM	191044
NCBI Accession	NP_000354.4 NM_000363.4
HGNC	11947
KEGG	hsa:7137
Ensembl	ENST00000344887, ENSP00000341838, ENSG00000129991
String	9606.ENSP00000341838
Molecular Weight	Observed MW: 24-26 kDa
Buffer	PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol.
Concentration	2 mg/ml
Availability	Shipped within 5-12 working days.
Note	This product is for research use only.

Research Articles on Troponin I, Cardiac Muscle (TNNI3)

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