Transient Receptor Potential Cation Channel Subfamily C Member 5 (TRPC5) Antibody

This gene belongs to the transient receptor family. It encodes one of the seven mammalian TRPC (transient receptor potential channel) proteins. The encoded protein is a multi-pass membrane protein and is thought to form a receptor-activated non-selective calcium permeant cation channel. The protein is active alone or as a heteromultimeric assembly with TRPC1, TRPC3, and TRPC4. It also interacts with multiple proteins including calmodulin, CABP1, enkurin, Na (+) H+ exchange regulatory factor (NHERF), interferon-induced GTP-binding protein (MX1), ring finger protein 24 (RNF24), and SEC14 domain and spectrin repeat-containing protein 1 (SESTD1).

Target	Transient Receptor Potential Cation Channel Subfamily C Member 5 (TRPC5)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB, IHC
Host	Rabbit
Recommended dilutions	WB: 1/1000, IHC-P: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 254-283 amino acids from the N-terminal region of human TRPC5.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q9UL62 (UniProt, ExPASy)
UniProt Secondary AC	B2RP53, O75233, Q5JXY8, Q9Y514
UniProt Entry Name	TRPC5_HUMAN
Gene Symbol	TRPC5
String	9606.ENSP00000262839
Molecular Weight	Calculated MW: 111 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Mouse and Rabbit TRPC5.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Transient Receptor Potential Cation Channel Subfamily C Member 5 (TRPC5)

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