Transient Receptor Potential Cation Channel Subfamily V Member 4 (TRPV4) Antibody

TRPV4 Antibody is a Rabbit Polyclonal antibody against TRPV4. This gene encodes a member of the OSM9-like transient receptor potential channel (OTRPC) subfamily in the transient receptor potential (TRP) superfamily of ion channels. The encoded protein is a Ca2+-permeable, nonselective cation channel that is thought to be involved in the regulation of systemic osmotic pressure. Mutations in this gene are the cause of spondylometaphyseal and metatropic dysplasia and hereditary motor and sensory neuropathy type IIC. Multiple transcript variants encoding different isoforms have been found for this gene.

Target	Transient Receptor Potential Cation Channel Subfamily V Member 4 (TRPV4)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	WB
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	A synthetic peptide corresponding to a sequence within amino acids 800-871 of human TRPV4.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q9HBA0 (UniProt, ExPASy)
UniProt Entry Name	TRPV4_HUMAN
Gene Symbol	TRPV4
GeneID	59341
OMIM	113500
NCBI Accession	NP_067638.3
HGNC	18083
KEGG	hsa:59341
Ensembl	ENSG00000111199
String	9606.ENSP00000406191
Molecular Weight	Calculated MW: 98 kDa Observed MW: 95 kDa
Buffer	PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Transient Receptor Potential Cation Channel Subfamily V Member 4 (TRPV4)

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