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Tuberous Sclerosis Protein 2 (TSC2) Antibody
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Catalogue No: abx031372
Price:
US$326.25
(Size: 80 µl)
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Mutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms.
Research Articles on Tuberous Sclerosis Protein 2 (TSC2)
| Target | Tuberous Sclerosis Protein 2 (TSC2) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/25. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 1397-1426 amino acids from the Central region of human TSC2. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P49815 (UniProt, ExPASy) |
| UniProt Entry Name | TSC2_HUMAN |
| NCBI Accession | NP_000539.2 NP_001070651.1 NP_001107854.1 |
| KEGG | hsa:7249 |
| String | 9606.ENSP00000219476 |
| Molecular Weight | Calculated MW: 201 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |
