+44 (0) 1223 755950
+1 832 327 7413
Tuberous Sclerosis Protein 2 (TSC2) Antibody
REQUEST MORE INFO
Catalogue No: abx031372
Price:
US$326.25
(Size: 80 µl)
Orders to United States ship from United States
Reviews: 
(0 Publications and Reviews)
(0 Publications and Reviews)
Click on the image to see the image legend
Mutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms.
Research Articles on Tuberous Sclerosis Protein 2 (TSC2)
| Target | Tuberous Sclerosis Protein 2 (TSC2) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/25. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 1397-1426 amino acids from the Central region of human TSC2. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P49815 (UniProt, ExPASy) |
| UniProt Entry Name | TSC2_HUMAN |
| NCBI Accession | NP_000539.2 NP_001070651.1 NP_001107854.1 |
| KEGG | hsa:7249 |
| String | 9606.ENSP00000219476 |
| Molecular Weight | Calculated MW: 201 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |