Tumor Susceptibility Gene 101 (TSG101) Antibody

TSG101 Antibody is a Rabbit Polyclonal antibody against TSG101. The protein encoded by this gene belongs to a group of apparently inactive homologs of ubiquitin-conjugating enzymes. The gene product contains a coiled-coil domain that interacts with stathmin, a cytosolic phosphoprotein implicated in tumorigenesis. The protein may play a role in cell growth and differentiation and act as a negative growth regulator. In vitro steady-state expression of this tumor susceptibility gene appears to be important for maintenance of genomic stability and cell cycle regulation. Mutations and alternative splicing in this gene occur in high frequency in breast cancer and suggest that defects occur during breast cancer tumorigenesis and/or progression. [provided by RefSeq, Jul 2008].

Target	Tumor Susceptibility Gene 101 (TSG101)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/1000, IF/ICC: 1/50-1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	A synthetic peptide corresponding to a sequence within amino acids 291-390 of human TSG101/VPS23.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q99816 (UniProt, ExPASy)
UniProt Secondary AC	Q9BUM5
UniProt Entry Name	TS101_HUMAN
Gene Symbol	TSG101
GeneID	7251
NCBI Accession	NP_006283.1
KEGG	hsa:7251
String	9606.ENSP00000251968
Molecular Weight	Calculated MW: 44 kDa Observed MW: 44 kDa
Buffer	PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Tumor Susceptibility Gene 101 (TSG101)

Write a review

Your Name

Your Email Address

PMID

DOI

Your Review

Rating

Continue