Tumor Susceptibility Gene 101 (TSG101) Antibody

Catalogue No: abx001823
Price: £120.00
(Size: 20 µl)
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TSG101 Antibody is a Rabbit Polyclonal antibody against TSG101. The protein encoded by this gene belongs to a group of apparently inactive homologs of ubiquitin-conjugating enzymes. The gene product contains a coiled-coil domain that interacts with stathmin, a cytosolic phosphoprotein implicated in tumorigenesis. The protein may play a role in cell growth and differentiation and act as a negative growth regulator. In vitro steady-state expression of this tumor susceptibility gene appears to be important for maintenance of genomic stability and cell cycle regulation. Mutations and alternative splicing in this gene occur in high frequency in breast cancer and suggest that defects occur during breast cancer tumorigenesis and/or progression. [provided by RefSeq, Jul 2008].

Target TSG101
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB, IHC, IF/ICC, IP
Host Rabbit
Recommended dilutions WB: 1/200 - 1/2000, IHC: 1/50 - 1/200, IF/ICC: 1/50 - 1/200, IP: 1/20 - 1/50. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant fusion protein of human TSG101.
Isotype IgG
Form Liquid
Purification Purified by affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q99816 (UniProt, ExPASy)
UniProt Secondary AC Q9BUM5
UniProt Entry Name TS101_HUMAN
Gene Symbol TSG101
GeneID 7251
KEGG hsa:7251
String 9606.ENSP00000251968
Molecular Weight Calculated MW: 31 kDa, 43 kDa
Observed MW: 48 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 0.5 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on TSG101

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