Dual Specificity Protein Kinase TTK (TTK) Antibody

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Catalogue No: abx001944
Price: US$203.00
(Size: 20 µl)

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Datasheet SDS
TTK Antibody is a Rabbit Polyclonal antibody against TTK. This gene encodes a dual specificity protein kinase with the ability to phosphorylate tyrosine, serine and threonine. Associated with cell proliferation, this protein is essential for chromosome alignment at the centromere during mitosis and is required for centrosome duplication. It has been found to be a critical mitotic checkpoint protein for accurate segregation of chromosomes during mitosis. Tumorigenesis may occur when this protein fails to degrade and produces excess centrosomes resulting in aberrant mitotic spindles. Alternative splicing results in multiple transcript variants.

Target Dual Specificity Protein Kinase TTK (TTK)
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB, IF/ICC
Host Rabbit
Recommended dilutions WB: 1/1000 - 1/5000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 536-789 of human TTK.
Isotype IgG
Form Liquid
Purification Purified by affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P33981 (UniProt, ExPASy)
UniProt Secondary AC A8K8U5, B2RDW2, E1P543, Q15272, Q5TCS0, Q9BW51, Q9NTM0
UniProt Entry Name TTK_HUMAN
Gene Symbol TTK
GeneID 7272
NCBI Accession NP_003309.2
KEGG hsa:7272
String 9606.ENSP00000358813
Molecular Weight Calculated MW: 97 kDa
Observed MW: 100 kDa
Buffer PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol.
Concentration > 0.2 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Dual Specificity Protein Kinase TTK (TTK)


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