Transthyretin (TTR) Antibody

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Catalogue No: abx032940
Price: US$326.25
(Size: 80 µl)

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WB analysis of (1) Human placenta lysate and (2) Human plasma lysate (20 µg/lane) using TTR antibody, followed by a Goat anti-Rabbit IgG H&L antibody conjugated to HRP (1/10000 dilution). Calculated MW: 16 kDa.
Transthyretin (TTR) Antibody Transthyretin (TTR) Antibody Transthyretin (TTR) Antibody Transthyretin (TTR) Antibody

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Documents

Datasheet SDS
Transthyretin (TTR) antibody is a Rabbit polyclonal against Transthyretin (TTR).

Transthyretin is one of the three prealbumins including alpha-1-antitrypsin, transthyretin and orosomucoid. Transthyretin is a carrier protein- it transports thyroid hormones in the plasma and cerebrospinal fluid, and also transports retinol (vitamin A) in the plasma. It consists of a tetramer of identical subunits. More than 80 different mutations in this gene have been reported, most mutations are related to amyloid deposition, affecting predominantly peripheral nerve and/or the heart, and a small portion of the gene mutations is non-amyloidogenic. The diseases caused by mutations include amyloidotic polyneuropathy, euthyroid hyperthyroxinaemia, amyloidotic vitreous opacities, cardiomyopathy, oculoleptomeningeal amyloidosis, meningocerebrovascular amyloidosis, carpal tunnel syndrome, etc.

Target Transthyretin (TTR)
Research Area Enzymes and Kinases, Tumor Immunity, Infection Immunity, Hormone Metabolism, Cancer
Clonality Polyclonal
Reactivity Human, Rat
Tested Applications ELISA, WB, IHC, IF/ICC, FCM
Host Rabbit
Recommended dilutions WB: 1/2000, IHC-P: 1/25, IF/ICC: 1/25, FCM: 1/25. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen KLH-conjugated synthetic peptide between 71-98 amino acids from the C-terminal region of Human TTR.
Isotype IgG
Form Liquid
Purification Purified through a protein A column, followed by peptide affinity purification.
Storage Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles.
Shelf Life 12 months.
UniProt Primary AC P02766 (UniProt, ExPASy)
UniProt Secondary AC Q549C7, Q6IB96, Q9UBZ6, Q9UCM9
UniProt Entry Name TTHY_HUMAN
Gene Symbol TTR
NCBI Accession NP_000362.1
KEGG hsa:7276
String 9606.ENSP00000237014
Molecular Weight Calculated MW: 15.9 kDa
Buffer PBS containing 0.09% sodium azide.
Specificity Predicted to react with Monkey TTR.
Concentration 0.45 mg/ml
Availability Shipped within 5-10 working days.
Note THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
Research Articles on Transthyretin (TTR)


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