Transthyretin (TTR) Antibody
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Catalogue No: abx001035
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US$348.00
(Size: 60 µl)
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Datasheet SDS
TTR Antibody is a Rabbit Polyclonal antibody against TTR. This gene encodes transthyretin, one of the three prealbumins including alpha-1-antitrypsin, transthyretin and orosomucoid. Transthyretin is a carrier protein; it transports thyroid hormones in the plasma and cerebrospinal fluid, and also transports retinol (vitamin A) in the plasma. The protein consists of a tetramer of identical subunits. More than 80 different mutations in this gene have been reported; most mutations are related to amyloid deposition, affecting predominantly peripheral nerve and/or the heart, and a small portion of the gene mutations is non-amyloidogenic. The diseases caused by mutations include amyloidotic polyneuropathy, euthyroid hyperthyroxinaemia, amyloidotic vitreous opacities, cardiomyopathy, oculoleptomeningeal amyloidosis, meningocerebrovascular amyloidosis, carpal tunnel syndrome, etc. [provided by RefSeq, Jan 2009].
Research Articles on Transthyretin (TTR)
| Target | Transthyretin (TTR) |
| Research Area | Enzymes and Kinases, Tumor Immunity, Infection Immunity, Hormone Metabolism, Cancer |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | IHC, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | IHC-P: 1/50 - 1/100, IF/ICC: 1/50 - 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein corresponding to human TTR |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P02766 (UniProt, ExPASy) |
| UniProt Secondary AC | Q549C7, Q6IB96, Q9UBZ6, Q9UCM9 |
| UniProt Entry Name | TTHY_HUMAN |
| Gene Symbol | TTR |
| GeneID | 7276 |
| NCBI Accession | NP_000362.1 |
| KEGG | hsa:7276 |
| String | 9606.ENSP00000237014 |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
