Tumor Necrosis Factor Receptor Superfamily Member 9 / CD137 (TNFRSF9) Antibody
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Catalogue No: abx219180
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US$420.50
(Size: 100 µg)
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Datasheet SDS
Tumor Necrosis Factor Receptor Superfamily Member 9 / CD137 (TNFRSF9) Antibody is a Rabbit Polyclonal antibody for the detection of CD137. The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contributes to the clonal expansion, survival, and development of T cells. It can also induce proliferation in peripheral monocytes, enhance T cell apoptosis induced by TCR/CD3 triggered activation, and regulate CD28 co-stimulation to promote Th1 cell responses. The expression of this receptor is induced by lymphocyte activation. TRAF adaptor proteins have been shown to bind to this receptor and transduce the signals leading to activation of NF-kappaB.
Research Articles on Tumor Necrosis Factor Receptor Superfamily Member 9 / CD137 (TNFRSF9)
| Target | Tumor Necrosis Factor Receptor Superfamily Member 9 / CD137 (TNFRSF9) |
| Research Area | Cellular Differentiation and Adhesion |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000, IHC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Tumor necrosis factor receptor superfamily member 9 |
| Isotype | IgG |
| Form | Liquid |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by immunogen affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | Q07011 (UniProt, ExPASy) |
| UniProt Entry Name | TNR9_HUMAN |
| Gene Symbol | TNFRSF9 |
| GeneID | 3604 |
| OMIM | 602250 |
| HGNC | 11924 |
| KEGG | hsa:3604 |
| Ensembl | ENSG00000049249 |
| String | 9606.ENSP00000478699 |
| Molecular Weight | Observed MW: 27 kDa |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Concentration | 2 mg/ml |
| Availability | Shipped within 5-12 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |