Tumor Necrosis Factor Receptor Superfamily Member 9 / CD137 (TNFRSF9) Antibody

Tumor Necrosis Factor Receptor Superfamily Member 9 / CD137 (TNFRSF9) Antibody is a Rabbit Polyclonal antibody for the detection of CD137.

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contributes to the clonal expansion, survival, and development of T cells. It can also induce proliferation in peripheral monocytes, enhance T cell apoptosis induced by TCR/CD3 triggered activation, and regulate CD28 co-stimulation to promote Th1 cell responses. The expression of this receptor is induced by lymphocyte activation. TRAF adaptor proteins have been shown to bind to this receptor and transduce the signals leading to activation of NF-kappaB.

Target	Tumor Necrosis Factor Receptor Superfamily Member 9 / CD137 (TNFRSF9)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	ELISA, WB, IHC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000, IHC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Tumor necrosis factor receptor superfamily member 9
Isotype	IgG
Form	Liquid
Purity	≥ 95% (SDS-PAGE)
Purification	Purified by immunogen affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Validity	12 months.
UniProt Primary AC	Q07011 (UniProt, ExPASy)
UniProt Entry Name	TNR9_HUMAN
Gene Symbol	TNFRSF9
GeneID	3604
OMIM	602250
HGNC	11924
KEGG	hsa:3604
Ensembl	ENSG00000049249
String	9606.ENSP00000478699
Molecular Weight	Observed MW: 27 kDa
Buffer	PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol.
Concentration	2 mg/ml
Availability	Shipped within 5-12 working days.
Note	This product is for research use only.

Research Articles on Tumor Necrosis Factor Receptor Superfamily Member 9 / CD137 (TNFRSF9)

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