Tyrosine Kinase 2 (TYK2) Antibody

TYK2 Antibody is a Rabbit Polyclonal antibody against TYK2. This gene encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E.

Target	Tyrosine Kinase 2 (TYK2)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IHC, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/100 - 1/500, IHC-P: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1102-1182 of human TYK2.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P29597 (UniProt, ExPASy)
UniProt Secondary AC	Q6QB10, Q96CH0
UniProt Entry Name	TYK2_HUMAN
Gene Symbol	TYK2
GeneID	7297
NCBI Accession	NP_003322.3
KEGG	hsa:7297
String	9606.ENSP00000431885
Molecular Weight	Calculated MW: 134 kDa Observed MW: 134 kDa
Buffer	PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Tyrosine Kinase 2 (TYK2)

Write a review

Your Name

Your Email Address

PMID

DOI

Your Review

Rating

Continue