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Tyrosinase (TYR) Antibody
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Catalogue No: abx001163
Price:
US$348.00
(Size: 60 µl)
Orders to United States ship from United States
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TYR Antibody is a Rabbit Polyclonal antibody against TYR. The enzyme encoded by this gene catalyzes the first 2 steps, and at least 1 subsequent step, in the conversion of tyrosine to melanin. The enzyme has both tyrosine hydroxylase and dopa oxidase catalytic activities, and requires copper for function. Mutations in this gene result in oculocutaneous albinism, and nonpathologic polymorphisms result in skin pigmentation variation. The human genome contains a pseudogene similar to the 3' half of this gene. [provided by RefSeq, Oct 2008].
Research Articles on Tyrosinase (TYR)
| Target | Tyrosinase (TYR) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000, IHC-P: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein corresponding to human TYR |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P14679 (UniProt, ExPASy) |
| UniProt Secondary AC | Q15675, Q15676, Q15680, Q8TAK4, Q9BYY0, Q9BZX1 |
| UniProt Entry Name | TYRO_HUMAN |
| Gene Symbol | TYR |
| GeneID | 7299 |
| NCBI Accession | NP_000363.1 |
| KEGG | hsa:7299 |
| String | 9606.ENSP00000263321 |
| Molecular Weight | Calculated MW: 42 kDa/60 kDa Observed MW: 80 kDa |
| Buffer | PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
