Tyrosine-Protein Kinase Receptor TYRO3 (TYRO3) Antibody
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Catalogue No: abx012308
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US$427.75
(Size: 100 µl)
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Datasheet SDS
Tyro3 (also known as Sky and Rse), with 890-amino acid protein (about 98kDa), belongs to the Axl/Tyro3 family of receptor tyrosine kinases, which also includes Axl and Mer.Gas6 (growth arrest-specific gene-6) is a ligand for all members of the Axl family and they play essential roles in spermatogenesis, immunoregulation, and phagocytosis.Tyro3 was expressed at high levels during postnatal development and in the adult in the cortex.Tyro3 and Gas6 have neurotrophic roles in the nervous system.In addition, the signalling interactions of Axl and Tyro3 may play roles in tumourigenesis, inflammation as well as other cell proliferative diseases.
Research Articles on Tyrosine-Protein Kinase Receptor TYRO3 (TYRO3)
| Target | Tyrosine-Protein Kinase Receptor TYRO3 (TYRO3) |
| Clonality | Monoclonal |
| Reactivity | Human |
| Tested Applications | ELISA, IF/ICC |
| Host | Mouse |
| Recommended dilutions | ELISA: 1/10000, IF/ICC: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Purified recombinant fragment of TYRO3 expressed in E. coli. |
| Isotype | IgG1 |
| Form | Liquid |
| Purification | Unpurified ascites. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | Q06418 (UniProt, ExPASy) |
| UniProt Secondary AC | O14953, Q86VR3 |
| UniProt Entry Name | TYRO3_HUMAN |
| Gene Symbol | TYRO3 |
| GeneID | 7301 |
| OMIM | 600341 |
| HGNC | 12446 |
| KEGG | hsa:7301 |
| Ensembl | ENSG00000092445 |
| String | 9606.ENSP00000263798 |
| Molecular Weight | 96 kDa |
| Buffer | Ascitic fluid containing 0.03% sodium azide. |
| Concentration | Not determined. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |