Splicing Factor U2AF 35 kDa Subunit (U2AF1) Antibody

Catalogue No: abx000973
Price: £120.00
(Size: 20 µl)
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U2AF1 Antibody is a Rabbit Polyclonal antibody against U2AF1. U2 auxiliary factor (U2AF), comprising a large and a small subunit, is a non-snRNP protein required for the binding of U2 snRNP to the pre-mRNA branch site. U2 (RNU2) small nuclear RNA auxiliary factor 1 (U2AF1,synonyms: RN, FP793, U2AF35, U2AFBP, RNU2AF1)is the small subunit which plays a critical role in both constitutive and enhancer-dependent RNA splicing by directly mediating interactions between the large subunit and proteins bound to the enhancers. The U2AF1 gene is localized to chromosome 21q22.3, which is the critical region for three diseases, progressive myoclonus epilepsy, autoimmune polyglandular disease type 1, and one form of bipolar affective disorder.

Target U2AF1
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB, IHC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IHC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human U2AF1.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q01081 (UniProt, ExPASy)
UniProt Secondary AC Q701P4, Q71RF1
UniProt Entry Name U2AF1_HUMAN
Gene Symbol U2AF1
GeneID 7307
KEGG hsa:102724594 hsa:7307
String 9606.ENSP00000485022
Molecular Weight Calculated MW: 8 kDa, 19 kDa, 27 kDa
Observed MW: 38 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Splicing Factor U2AF 35 kDa Subunit (U2AF1) Antibody

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