Splicing Factor U2AF 35 kDa Subunit (U2AF1) Antibody

U2AF1 Antibody is a Rabbit Polyclonal antibody against U2AF1. U2 auxiliary factor (U2AF), comprising a large and a small subunit, is a non-snRNP protein required for the binding of U2 snRNP to the pre-mRNA branch site. U2 (RNU2) small nuclear RNA auxiliary factor 1 (U2AF1,synonyms: RN, FP793, U2AF35, U2AFBP, RNU2AF1)is the small subunit which plays a critical role in both constitutive and enhancer-dependent RNA splicing by directly mediating interactions between the large subunit and proteins bound to the enhancers. The U2AF1 gene is localized to chromosome 21q22.3, which is the critical region for three diseases, progressive myoclonus epilepsy, autoimmune polyglandular disease type 1, and one form of bipolar affective disorder.

Target	Splicing Factor U2AF 35 kDa Subunit (U2AF1)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IHC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000, IHC-P: 1/50 - 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human U2AF1.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q01081 (UniProt, ExPASy)
UniProt Secondary AC	Q701P4, Q71RF1
UniProt Entry Name	U2AF1_HUMAN
Gene Symbol	U2AF1
GeneID	7307
NCBI Accession	NP_006749.1
KEGG	hsa:102724594 hsa:7307
String	9606.ENSP00000485022
Molecular Weight	Calculated MW: 28 kDa Observed MW: 38 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Splicing Factor U2AF 35 kDa Subunit (U2AF1)

Write a review

Your Name

Your Email Address

PMID

DOI

Your Review

Rating

Continue