Splicing Factor U2AF 35 kDa Subunit (U2AF1) Antibody

U2AF1 Antibody is a Rabbit Monoclonal antibody against U2AF1. This gene belongs to the splicing factor SR family of genes. U2 auxiliary factor, comprising a large and a small subunit, is a non-snRNP protein required for the binding of U2 snRNP to the pre-mRNA branch site. This gene encodes the small subunit which plays a critical role in both constitutive and enhancer-dependent RNA splicing by directly mediating interactions between the large subunit and proteins bound to the enhancers. Alternatively spliced transcript variants encoding different isoforms have been identified.

Target	Splicing Factor U2AF 35 kDa Subunit (U2AF1)
Clonality	Monoclonal
Reactivity	Human
Tested Applications	WB
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human U2AF1.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q01081 (UniProt, ExPASy)
UniProt Secondary AC	Q701P4, Q71RF1
UniProt Entry Name	U2AF1_HUMAN
Gene Symbol	U2AF1
GeneID	7307
NCBI Accession	NP_006749.1
KEGG	hsa:102724594 hsa:7307
String	9606.ENSP00000485022
Molecular Weight	Calculated MW: 28 kDa Observed MW: 38 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Splicing Factor U2AF 35 kDa Subunit (U2AF1)

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