U2 Small Nuclear RNA Auxiliary Factor 2 (U2AF2) Antibody

U2AF2 Antibody is a Rabbit Polyclonal antibody against U2AF2. U2 auxiliary factor (U2AF), comprised of a large and a small subunit, is a non-snRNP protein required for the binding of U2 snRNP to the pre-mRNA branch site. This gene encodes the U2AF large subunit which contains a sequence-specific RNA-binding region with 3 RNA recognition motifs and an Arg/Ser-rich domain necessary for splicing. The large subunit binds to the polypyrimidine tract of introns early during spliceosome assembly. Multiple transcript variants have been detected for this gene, but the full-length natures of only two have been determined to date.

Target	U2 Small Nuclear RNA Auxiliary Factor 2 (U2AF2)
Clonality	Polyclonal
Reactivity	Human, Mouse
Tested Applications	WB, IF/ICC, IP
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000, IF/ICC: 1/50 - 1/100, IP: 0.5-4 µg/200-400 µg whole cell extracts. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 192-471 of human U2AF2/U2AF65.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P26368 (UniProt, ExPASy)
UniProt Secondary AC	Q96HC5
UniProt Entry Name	U2AF2_HUMAN
Gene Symbol	U2AF2
GeneID	11338
NCBI Accession	NP_001012496.1
KEGG	hsa:11338
String	9606.ENSP00000307863
Molecular Weight	Calculated MW: 54 kDa Observed MW: 54 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on U2 Small Nuclear RNA Auxiliary Factor 2 (U2AF2)

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