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Ubiquitin Carrier Protein 9 (UBC9) Antibody
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Catalogue No: abx025821
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US$326.25
(Size: 80 µl)
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Datasheet SDS
UBE2I (Ubc9) is a member of the E2 family and is specific for the conjugation of SUMO to a variety of target proteins. SUMO conjugation to target proteins is mediated by a different, but analogous, pathway to ubiquitinylation. This E2 is unusual in that it interacts directly with protein substrates that are modified by sumoylation, and may play a role in substrate recognition. UBE2I can mediate the conjugation of SUMO-1 to a variety of proteins including RanGAP1, I?B?, and PML without the requirement of an E3 ligase. UBE2I is essential for nuclear architecture and chromosome segregation.
Research Articles on Ubiquitin Carrier Protein 9 (UBC9)
| Target | Ubiquitin Carrier Protein 9 (UBC9) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/50 - 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human UBC9 (UBE2I). |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P63279 (UniProt, ExPASy) |
| UniProt Secondary AC | D3DU69, P50550, Q15698, Q59GX1, Q86VB3 |
| UniProt Entry Name | UBC9_HUMAN |
| NCBI Accession | NP_003336.1 NP_919235.1 NP_919236.1 NP_919237.1 |
| KEGG | hsa:7329 |
| String | 9606.ENSP00000348056 |
| Molecular Weight | Calculated MW: 18 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Mouse, Rat, Zebrafish and Xenopus UBE2I. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |