Ubiquitin Conjugating Enzyme E2C (UBE2C) Antibody

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UBE2C is a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is required for the destruction of mitotic cyclins and for cell cycle progression.

Target	Ubiquitin Conjugating Enzyme E2C (UBE2C)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB
Host	Rabbit
Recommended dilutions	WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 10-39 amino acids from the N-terminal region of human UBE2C.
Isotype	IgG
Form	Liquid
Purification	Purified Rabbit Polyclonal Antibody.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	O00762 (UniProt, ExPASy)
UniProt Secondary AC	A6NP33, E1P5N7, G3XAB7
UniProt Entry Name	UBE2C_HUMAN
Gene Symbol	UBE2C
KEGG	hsa:11065
String	9606.ENSP00000348838
Molecular Weight	Calculated MW: 19.7 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Mouse, Cow and Monkey UBE2C.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Ubiquitin Conjugating Enzyme E2C (UBE2C)

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