Ubiquitin-Conjugating Enzyme E2 D1 (UBE2D1) Antibody

Catalogue No: abx001594
Price: £120.00
(Size: 20 µl)
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Ubiquitin-Conjugating Enzyme E2 D1 (UBE2D1) Antibody Ubiquitin-Conjugating Enzyme E2 D1 (UBE2D1) Antibody Ubiquitin-Conjugating Enzyme E2 D1 (UBE2D1) Antibody Ubiquitin-Conjugating Enzyme E2 D1 (UBE2D1) Antibody

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UBE2D1 Antibody is a Rabbit Polyclonal antibody against UBE2D1. The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is closely related to a stimulator of iron transport (SFT), and is up-regulated in hereditary hemochromatosis. It also functions in the ubiquitination of the tumor-suppressor protein p53 and the hypoxia-inducible transcription factor HIF1alpha by interacting with the E1 ubiquitin-activating enzyme and the E3 ubiquitin-protein ligases. Two transcript variants encoding different isoforms have been found for this gene.

Target UBE2D1
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB, IHC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IHC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-147 of human UBE2D1 (NP_003329.1).
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P51668 (UniProt, ExPASy)
UniProt Secondary AC A6NLF6, A8K786
UniProt Entry Name UB2D1_HUMAN
Gene Symbol UBE2D1
GeneID 7321
KEGG hsa:7321
String 9606.ENSP00000363019
Molecular Weight Calculated MW: 16 kDa
Observed MW: 14 kDa
Buffer PBS, pH 7.3, 50% glycerol.
Concentration 1.37 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Ubiquitin-Conjugating Enzyme E2 D1 (UBE2D1) Antibody

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