Ubiquitin-Conjugating Enzyme E2 D1 (UBE2D1) Antibody

UBE2D1 Antibody is a Rabbit Polyclonal antibody against UBE2D1. The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is closely related to a stimulator of iron transport (SFT), and is up-regulated in hereditary hemochromatosis. It also functions in the ubiquitination of the tumor-suppressor protein p53 and the hypoxia-inducible transcription factor HIF1alpha by interacting with the E1 ubiquitin-activating enzyme and the E3 ubiquitin-protein ligases. Two transcript variants encoding different isoforms have been found for this gene.

Target	Ubiquitin-Conjugating Enzyme E2 D1 (UBE2D1)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IHC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000, IHC-P: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-147 of human UBE2D1.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P51668 (UniProt, ExPASy)
UniProt Secondary AC	A6NLF6, A8K786
UniProt Entry Name	UB2D1_HUMAN
Gene Symbol	UBE2D1
GeneID	7321
NCBI Accession	NP_003329.1
KEGG	hsa:7321
String	9606.ENSP00000363019
Molecular Weight	Calculated MW: 17 kDa Observed MW: 14 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	1.37 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Ubiquitin-Conjugating Enzyme E2 D1 (UBE2D1)

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