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Ubiquitin-Conjugating Enzyme E2 D1 (UBE2D1) Antibody
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Catalogue No: abx001594
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US$348.00
(Size: 60 µl)
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Datasheet SDS
UBE2D1 Antibody is a Rabbit Polyclonal antibody against UBE2D1. The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is closely related to a stimulator of iron transport (SFT), and is up-regulated in hereditary hemochromatosis. It also functions in the ubiquitination of the tumor-suppressor protein p53 and the hypoxia-inducible transcription factor HIF1alpha by interacting with the E1 ubiquitin-activating enzyme and the E3 ubiquitin-protein ligases. Two transcript variants encoding different isoforms have been found for this gene.
Research Articles on Ubiquitin-Conjugating Enzyme E2 D1 (UBE2D1)
| Target | Ubiquitin-Conjugating Enzyme E2 D1 (UBE2D1) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000, IHC-P: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein corresponding to human UBE2D1 |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P51668 (UniProt, ExPASy) |
| UniProt Secondary AC | A6NLF6, A8K786 |
| UniProt Entry Name | UB2D1_HUMAN |
| Gene Symbol | UBE2D1 |
| GeneID | 7321 |
| NCBI Accession | NP_003329.1 |
| KEGG | hsa:7321 |
| String | 9606.ENSP00000363019 |
| Molecular Weight | Calculated MW: 16 kDa Observed MW: 14 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
