Ubiquitin-Conjugating Enzyme E2 L3 (UBE2L3) Antibody

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is demonstrated to participate in the ubiquitination of p53, c-Fos, and the NF-kB precursor p105 in vitro. Several alternatively spliced transcript variants have been found for this gene.

Target	Ubiquitin-Conjugating Enzyme E2 L3 (UBE2L3)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	ELISA, WB, IHC
Host	Rabbit
Recommended dilutions	WB: 1/1000, IHC-P: 1/25. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 106-135 amino acids from the C-terminal region of human UBE2L3.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P68036 (UniProt, ExPASy)
UniProt Secondary AC	B2R4A7, B4DDG1, B4DSZ4, E7EWS7, P51966, P70653, Q9HAV1
UniProt Entry Name	UB2L3_HUMAN
NCBI Accession	NP_001243284.1 NP_001243285.1 NP_003338.1
KEGG	hsa:7332
String	9606.ENSP00000485133
Molecular Weight	Calculated MW: 17.9 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Cow UBE2L3.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Ubiquitin-Conjugating Enzyme E2 L3 (UBE2L3)

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