Ubiquitin Conjugation Factor E4 A (UBE4A) Antibody

UBE4A Antibody is a Rabbit Polyclonal antibody against UBE4A. This gene encodes a member of the U-box ubiquitin ligase family. The encoded protein is involved in multiubiquitin chain assembly and plays a critical role in chromosome condensation and separation through the polyubiquitination of securin. Autoantibodies against the encoded protein may be markers for scleroderma and Crohn's disease. A pseudogene of this gene is located on the long arm of chromosome 3. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Target	Ubiquitin Conjugation Factor E4 A (UBE4A)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IHC
Host	Rabbit
Recommended dilutions	WB: 1/1000 - 1/5000, IHC-P: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 797-1066 of human UBE4A.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q14139 (UniProt, ExPASy)
UniProt Secondary AC	B0YJB6, Q2M1H0, Q6P5T4, Q7Z639
UniProt Entry Name	UBE4A_HUMAN
Gene Symbol	UBE4A
GeneID	9354
NCBI Accession	NP_001191006.1
KEGG	hsa:9354
String	9606.ENSP00000387362
Molecular Weight	Calculated MW: 123 kDa Observed MW: 123 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Ubiquitin Conjugation Factor E4 A (UBE4A)

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