Ubiquitin B Antibody

Catalogue No: abx000577
Price: £260.00
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Ubiquitin B Antibody

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Ubiquitin B Antibody is a Rabbit Polyclonal antibody against Ubiquitin B. This gene encodes ubiquitin, one of the most conserved proteins known. Ubiquitin has a major role in targeting cellular proteins for degradation by the 26S proteosome. It is also involved in the maintenance of chromatin structure, the regulation of gene expression, and the stress response. Ubiquitin is synthesized as a precursor protein consisting of either polyubiquitin chains or a single ubiquitin moiety fused to an unrelated protein. This gene consists of three direct repeats of the ubiquitin coding sequence with no spacer sequence. Consequently, the protein is expressed as a polyubiquitin precursor with a final amino acid after the last repeat. An aberrant form of this protein has been detected in patients with Alzheimer's disease and Down syndrome. Pseudogenes of this gene are located on chromosomes 1, 2, 13, and 17. Alternative splicing results in multiple transcript variants.

Target Ubiquitin B
Reactivity Human, Mouse, Rat
Origin Human
Host Rabbit
Clonality Polyclonal
Tested Applications WB, IHC, IF/ICC, FCM
Recommended dilutions WB: 1/1000 - 1/2000, IHC: 1/100 - 1/200, IF/ICC: 1/100 - 1/200, FCM: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Immunogen A synthetic peptide of human Ubiquitin B.
Purification Affinity purified.
Isotype IgG
Conjugation Unconjugated
Storage Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.
Molecular Weight 8 kDa
Swiss Prot P0CG47
GeneID 7314
Gene Symbol UBB
Concentration > 1 mg/ml
Buffer PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Availability Shipped within 5-10 working days.
Note This product is for research use only.

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