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Ubiquitin Carboxyl-Terminal Hydrolase 11 (USP11) Antibody
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Catalogue No: abx149788
Price:
US$406.00
(Size: 100 µg)
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Ubiquitin Carboxyl-Terminal Hydrolase 11 (USP11) Antibody is a Rabbit Polyclonal antibody for the detection of USP11. Protease that can remove conjugated ubiquitin from target proteins and polyubiquitin chains (PubMed:12084015, PubMed:15314155, PubMed:17897950, PubMed:19874889, PubMed:20233726, PubMed:24724799). Inhibits the degradation of target proteins by the proteasome (PubMed:12084015). Cleaves preferentially 'Lys-6' and 'Lys-63'-linked ubiquitin chains. Has lower activity with 'Lys-11' and 'Lys-33'-linked ubiquitin chains, and extremely low activity with 'Lys-27', 'Lys-29' and 'Lys-48'-linked ubiquitin chains (in vitro) (PubMed:24724799). Plays a role in the regulation of pathways leading to NF-kappa-B activation (PubMed:17897950, PubMed:19874889). Plays a role in the regulation of DNA repair after double-stranded DNA breaks (PubMed:15314155, PubMed:20233726).
Research Articles on Ubiquitin Carboxyl-Terminal Hydrolase 11 (USP11)
| Target | Ubiquitin Carboxyl-Terminal Hydrolase 11 (USP11) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC, IP |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/1000, IHC: 1/50 - 1/500, IP: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | ubiquitin specific peptidase 11 |
| Isotype | IgG |
| Form | Liquid |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by immunogen affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Validity | 12 months. |
| UniProt Primary AC | P51784 (UniProt, ExPASy) |
| UniProt Secondary AC | B2RTX1, Q8IUG6, Q9BWE1 |
| UniProt Entry Name | UBP11_HUMAN |
| Gene Symbol | USP11 |
| GeneID | 8237 |
| OMIM | 300050 |
| HGNC | 12609 |
| Ensembl | ENSG00000102226 |
| String | 9606.ENSP00000218348 |
| Molecular Weight | Observed MW: 110 kDa |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Concentration | 2 mg/ml |
| Availability | Shipped within 5-12 working days. |
| Note | This product is for research use only. |
