Upstream-Binding Protein 1 (UBP1) Antibody

UBP1 functions as a transcriptional activator in a promoter context-dependent manner. Modulates the placental expression of CYP11A1. Involved in regulation of the alpha-globin gene in erythroid cells. Activation of the alpha-globin promoter in erythroid cells is via synergistic interaction with TFCP2 (By similarity). Involved in regulation of the alpha-globin gene in erythroid cells. Binds strongly to sequences around the HIV-1 initiation site and weakly over the TATA-box. Represses HIV-1 transcription by inhibiting the binding of TFIID to the TATA-box.

Target	Upstream-Binding Protein 1 (UBP1)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB, IHC, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/1000, IHC-P: 1/10 - 1/50, IF/ICC: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 266-295 amino acids from the Central region of human UBP1.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q9NZI7 (UniProt, ExPASy)
UniProt Secondary AC	Q68CT0, Q86Y57, Q9H8V0, Q9UD76, Q9UD78
UniProt Entry Name	UBIP1_HUMAN
Gene Symbol	UBP1
String	9606.ENSP00000283629
Molecular Weight	Calculated MW: 60.5 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Mouse UBP1.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Upstream-Binding Protein 1 (UBP1)

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