Mitochondrial Brown Fat Uncoupling Protein 1 (UCP1) Antibody

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Catalogue No: abx004494
Price: US$203.00
(Size: 20 µl)

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Datasheet SDS
UCP1 Antibody is a Rabbit Polyclonal antibody against UCP1. Mitochondrial uncoupling proteins (UCP) are members of the family of mitochondrial anion carrier proteins (MACP). UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. Tissue specificity occurs for the different UCPs and the exact methods of how UCPs transfer H+/OH- are not known. UCPs contain the three homologous protein domains of MACPs. This gene is expressed only in brown adipose tissue, a specialized tissue which functions to produce heat.

Target Mitochondrial Brown Fat Uncoupling Protein 1 (UCP1)
Clonality Polyclonal
Reactivity Mouse, Rat
Tested Applications WB, IHC, IF/ICC
Host Rabbit
Recommended dilutions WB: 1/100 - 1/500, IHC-P: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant Protein corresponding to a sequence within amino acids 1-307 of human UCP1.
Isotype IgG
Form Liquid
Purification Purified by affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P25874 (UniProt, ExPASy)
UniProt Secondary AC Q13218, Q4KMZ3, Q68G66
UniProt Entry Name UCP1_HUMAN
Gene Symbol UCP1
GeneID 7350
NCBI Accession NP_068605.1
KEGG hsa:7350
String 9606.ENSP00000262999
Molecular Weight Calculated MW: 33 kDa
Observed MW: 33 kDa
Buffer PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol.
Concentration > 0.2 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Mitochondrial Brown Fat Uncoupling Protein 1 (UCP1)


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