Mitochondrial Uncoupling Protein 2 (UCP2) Antibody

Catalogue No: abx003088
Price: £120.00
(Size: 20 µl)
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UCP2 Antibody is a Rabbit Polyclonal antibody against UCP2. Mitochondrial uncoupling proteins (UCP) are members of the larger family of mitochondrial anion carrier proteins (MACP). UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. Tissue specificity occurs for the different UCPs and the exact methods of how UCPs transfer H+/OH- are not known. UCPs contain the three homologous protein domains of MACPs. This gene is expressed in many tissues, with the greatest expression in skeletal muscle. It is thought to play a role in nonshivering thermogenesis, obesity and diabetes. Chromosomal order is 5'-UCP3-UCP2-3'.

Target Mitochondrial Uncoupling Protein 2 (UCP2)
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human UCP2.
Isotype IgG
Form Liquid
Purification Purified by affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P55851 (UniProt, ExPASy)
UniProt Secondary AC Q4PJH8, Q53HM3
UniProt Entry Name UCP2_HUMAN
Gene Symbol UCP2
GeneID 7351
KEGG hsa:7351
String 9606.ENSP00000312029
Molecular Weight Calculated MW: 33 kDa
Observed MW: 30 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 0.5 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Mitochondrial Uncoupling Protein 2 (UCP2)

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