Mitochondrial Uncoupling Protein 3 (UCP3) Antibody

Catalogue No: abx001290
Price: £120.00
(Size: 20 µl)

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Datasheet SDS
UCP3 Antibody is a Rabbit Polyclonal antibody against UCP3. The uncoupling protein UCP1 (formerly designated UCP) is an integral membrane protein unique to brown adipose tissue mitochondria. UCP1 forms a dimer that acts as a proton channel, which can uncouple oxidative phosphorylation by dissipating the electrochemical potential across the inner mitochondrial membrane. This process induces heat production in brown adipose tissue and is involved in regulation of body temperature and glucose metabolism. UCP2 is a structurally related protein that also uncouples mitochondrial respiration. It is more widely expressed in human and mouse tissues, including white adipose tissue and muscle, than is UCP1. UCP2 is thought to play a role in body weight regulation. An additional UCP family member, UCP3, is highly muscle specific and is possibly involved in the uncoupling of oxidative phosphorylation in skeletal muscle.

Target UCP3
Clonality Polyclonal
Reactivity Human, Mouse
Tested Applications WB
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human UCP3.
Isotype IgG
Form Liquid
Purification Purified by affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P55916 (UniProt, ExPASy)
UniProt Secondary AC O60475, Q96HL3
UniProt Entry Name UCP3_HUMAN
Gene Symbol UCP3
GeneID 7352
KEGG hsa:7352
String 9606.ENSP00000323740
Molecular Weight Calculated MW: 22 kDa, 29 kDa, 34 kDa
Observed MW: 25 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 0.5 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on UCP3

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