Ubiquitin Like With PHD And Ring Finger Domains 1 (UHRF1) Antibody

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Catalogue No: abx034132
Price: US$326.25
(Size: 80 µl)

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Ubiquitin Like With PHD And Ring Finger Domains 1 (UHRF1) Antibody Ubiquitin Like With PHD And Ring Finger Domains 1 (UHRF1) Antibody Ubiquitin Like With PHD And Ring Finger Domains 1 (UHRF1) Antibody

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Documents

Datasheet SDS
UHRF1 is a member of a subfamily of RING-finger type E3 ubiquitin ligases. The protein binds to specific DNA sequences, and recruits a histone acetylase to regulate gene expression. Its expression peaks at late G1 phase and continues during G2 and M phases of the cell cycle. It plays a major role in the G1/S transition by regulating topoisomerase IIalpha and retinoblastoma gene expression, and functions in the p53-dependent DNA damage checkpoint.

Target Ubiquitin Like With PHD And Ring Finger Domains 1 (UHRF1)
Clonality Polyclonal
Reactivity Human
Tested Applications ELISA, WB, IF/ICC, FCM
Host Rabbit
Recommended dilutions WB: 1/1000, IF/ICC: 1/10 - 1/50, FCM: 1/10 - 1/50. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen KLH-conjugated synthetic peptide between 229-257 amino acids from the Central region of human UHRF1.
Isotype IgG
Form Liquid
Purification Purified through a protein A column, followed by peptide affinity purification.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q96T88 (UniProt, ExPASy)
UniProt Entry Name UHRF1_HUMAN
Gene Symbol UHRF1
NCBI Accession NP_001041666.1 NP_037414.3
KEGG hsa:29128
String 9606.ENSP00000479617
Molecular Weight Calculated MW: 89.8 kDa
Buffer PBS containing 0.09% sodium azide.
Availability Shipped within 5-10 working days.
Note THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
Research Articles on Ubiquitin Like With PHD And Ring Finger Domains 1 (UHRF1)


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