Ubiquitin Like With PHD And Ring Finger Domains 1 (UHRF1) Antibody

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Catalogue No: abx001900
Price: US$203.00
(Size: 20 µl)

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Datasheet SDS
UHRF1 Antibody is a Rabbit Polyclonal antibody against UHRF1. UHRF1, also named as ICBP90, NP95 and RNF106, is a putative E3 ubiquitin-protein ligase. It may participate in methylation-dependent transcriptional regulation. UHRF1 binds to inverted 5'-CCAAT-3' box 2 in the TOP2A promoter, and activates TOP2A expression. It is important for G1/S transition and may be involved in DNA repair and chromosomal stability. UHRF1's ability to repress its direct target gene expression is dependent on PHD(UHRF1) binding to unmodified H3R2.

Target Ubiquitin Like With PHD And Ring Finger Domains 1 (UHRF1)
Clonality Polyclonal
Reactivity Human, Mouse
Tested Applications WB
Host Rabbit
Recommended dilutions WB: 1/100 - 1/500. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human UHRF1.
Isotype IgG
Form Liquid
Purification Purified by affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q96T88 (UniProt, ExPASy)
UniProt Entry Name UHRF1_HUMAN
Gene Symbol UHRF1
GeneID 29128
NCBI Accession NP_001041666.1
KEGG hsa:29128
String 9606.ENSP00000479617
Molecular Weight Calculated MW: 90 kDa
Observed MW: 95 kDa
Buffer PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration > 0.2 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Ubiquitin Like With PHD And Ring Finger Domains 1 (UHRF1)


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