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Ubiquitin Like With PHD And Ring Finger Domains 1 (UHRF1) Antibody

Catalogue No: abx001900
Price: £120.00
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Ubiquitin Like With PHD And Ring Finger Domains 1 (UHRF1) Antibody Ubiquitin Like With PHD And Ring Finger Domains 1 (UHRF1) Antibody Ubiquitin Like With PHD And Ring Finger Domains 1 (UHRF1) Antibody Ubiquitin Like With PHD And Ring Finger Domains 1 (UHRF1) Antibody Ubiquitin Like With PHD And Ring Finger Domains 1 (UHRF1) Antibody Ubiquitin Like With PHD And Ring Finger Domains 1 (UHRF1) Antibody Ubiquitin Like With PHD And Ring Finger Domains 1 (UHRF1) Antibody

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UHRF1 Antibody is a Rabbit Polyclonal antibody against UHRF1. UHRF1, also named as ICBP90, NP95 and RNF106, is a putative E3 ubiquitin-protein ligase. It may participate in methylation-dependent transcriptional regulation. UHRF1 binds to inverted 5'-CCAAT-3' box 2 in the TOP2A promoter, and activates TOP2A expression. It is important for G1/S transition and may be involved in DNA repair and chromosomal stability. UHRF1's ability to repress its direct target gene expression is dependent on PHD(UHRF1) binding to unmodified H3R2.

Target UHRF1
Clonality Polyclonal
Reactivity Human
Tested Applications WB, IHC, IF/ICC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IHC: 1/50 - 1/200, IF/ICC: 1/20 - 1/50. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human UHRF1.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q96T88 (UniProt, ExPASy)
UniProt Entry Name UHRF1_HUMAN
Gene Symbol UHRF1
GeneID 29128
KEGG hsa:29128
String 9606.ENSP00000479617
Molecular Weight Calculated MW: 89 kDa, 91 kDa
Observed MW: 110 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Ubiquitin Like With PHD And Ring Finger Domains 1 (UHRF1) Antibody

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