Uromodulin (UMOD) Antibody

Catalogue No: abx001568
Price: £120.00
(Size: 20 µl)
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Uromodulin (UMOD) Antibody

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UMOD Antibody is a Rabbit Polyclonal antibody against UMOD. The protein encoded by this gene is the most abundant protein in mammalian urine under physiological conditions. Its excretion in urine follows proteolytic cleavage of the ectodomain of its glycosyl phosphatidylinosital-anchored counterpart that is situated on the luminal cell surface of the loop of Henle. This protein may act as a constitutive inhibitor of calcium crystallization in renal fluids. Excretion of this protein in urine may provide defense against urinary tract infections caused by uropathogenic bacteria. Defects in this gene are associated with the renal disorders medullary cystic kidney disease-2 (MCKD2), glomerulocystic kidney disease with hyperuricemia and isosthenuria (GCKDHI), and familial juvenile hyperuricemic nephropathy (FJHN). Alternative splicing of this gene results in multiple transcript variants.

Target Uromodulin (UMOD)
Clonality Polyclonal
Reactivity Human, Mouse
Tested Applications WB
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human UMOD.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P07911 (UniProt, ExPASy)
UniProt Secondary AC B3KP48, B3KRN9, E9PEA4, Q540J6, Q6ZS84, Q8IYG0
UniProt Entry Name UROM_HUMAN
Gene Symbol UMOD
GeneID 7369
KEGG hsa:7369
String 9606.ENSP00000379438
Molecular Weight Calculated MW: 55 kDa, 66 kDa, 67 kDa, 69 kDa, 73 kDa
Observed MW: 70 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration 1.52 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Uromodulin (UMOD) Antibody

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