Protein Unc-13 Homolog B (UNC13B) Antibody
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Catalogue No: abx034150
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US$326.25
(Size: 80 µl)
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Datasheet SDS
UNC13B plays a role in vesicle maturation during exocytosis as a target of the diacylglycerol second messenger pathway. It is involved in neurotransmitter release by acting in synaptic vesicle priming prior to vesicle fusion and participates in the activity-depending refilling of readily releasable vesicle pool (RRP). It is essential for synaptic vesicle maturation in a subset of excitatory/glutamatergic but not inhibitory/GABA-mediated synapses (By similarity).
Research Articles on Protein Unc-13 Homolog B (UNC13B)
| Target | Protein Unc-13 Homolog B (UNC13B) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, FCM |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, FCM: 1/10 - 1/50. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 1062-1091 amino acids from the Central region of human UNC13B. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | O14795 (UniProt, ExPASy) |
| UniProt Secondary AC | Q2NKJ5, Q5VYM8 |
| UniProt Entry Name | UN13B_HUMAN |
| Gene Symbol | UNC13B |
| KEGG | hsa:10497 |
| String | 9606.ENSP00000367756 |
| Molecular Weight | Calculated MW: 181 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Mouse UNC13B. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |