Protein Unc-13 Homolog B (UNC13B) Antibody

UNC13B plays a role in vesicle maturation during exocytosis as a target of the diacylglycerol second messenger pathway. It is involved in neurotransmitter release by acting in synaptic vesicle priming prior to vesicle fusion and participates in the activity-depending refilling of readily releasable vesicle pool (RRP). It is essential for synaptic vesicle maturation in a subset of excitatory/glutamatergic but not inhibitory/GABA-mediated synapses (By similarity).

Target	Protein Unc-13 Homolog B (UNC13B)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB, FCM
Host	Rabbit
Recommended dilutions	WB: 1/1000, FCM: 1/10 - 1/50. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 1062-1091 amino acids from the Central region of human UNC13B.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	O14795 (UniProt, ExPASy)
UniProt Secondary AC	Q2NKJ5, Q5VYM8
UniProt Entry Name	UN13B_HUMAN
Gene Symbol	UNC13B
KEGG	hsa:10497
String	9606.ENSP00000367756
Molecular Weight	Calculated MW: 181 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Mouse UNC13B.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Protein Unc-13 Homolog B (UNC13B)

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