Netrin Receptor UNC5C (UNC5C) Antibody
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Catalogue No: abx033065
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US$326.25
(Size: 80 µl)
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Datasheet SDS
UNC5C belongs to the UNC-5 family of netrin receptors. Netrins are secreted proteins that direct axon extension and cell migration during neural development. They are bifunctional proteins that act as attractants for some cell types and as repellents for others, and these opposite actions are thought to be mediated by two classes of receptors. The UNC-5 family of receptors mediate the repellent response to netrin; they are transmembrane proteins containing 2 immunoglobulin (Ig) like domains and 2 type I thrombospondin motifs in the extracellular region.
Research Articles on Netrin Receptor UNC5C (UNC5C)
| Target | Netrin Receptor UNC5C (UNC5C) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC, FCM |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/50 - 1/100, FCM: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 188-217 amino acids from the Central region of human UNC5C. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | O95185 (UniProt, ExPASy) |
| UniProt Secondary AC | Q8IUT0 |
| UniProt Entry Name | UNC5C_HUMAN |
| Gene Symbol | UNC5C |
| KEGG | hsa:8633 |
| String | 9606.ENSP00000406022 |
| Molecular Weight | Calculated MW: 103 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Rat UNC5C. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |