Protein Unc-84 Homolog B (UNC84B) Antibody

SUN1 (MIM 607723) and SUN2 are inner nuclear membrane (INM) proteins that play a major role in nuclear-cytoplasmic connection by formation of a 'bridge' across the nuclear envelope, known as the LINC complex, via interaction with the conserved luminal KASH domain of nesprins (e.g., SYNE1; MIM 608441) located in the outer nuclear membrane (ONM). The LINC complex provides a direct connection between the nuclear lamina and the cytoskeleton, which contributes to nuclear positioning and cellular rigidity (summary by Haque et al., 2010 [PubMed 19933576]).[supplied by OMIM].

Target	Protein Unc-84 Homolog B (UNC84B)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB
Host	Rabbit
Recommended dilutions	WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 237-265 amino acids from the Central region of human UNC84B.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q9UH99 (UniProt, ExPASy)
UniProt Secondary AC	B0QY62, O75156, Q2NKN8, Q2T9F7, Q504T5, Q6B4H1, Q7Z3E3
UniProt Entry Name	SUN2_HUMAN
Gene Symbol	SUN2
String	9606.ENSP00000385616
Molecular Weight	Calculated MW: 80.3 kDa
Buffer	PBS containing 0.09% sodium azide.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Protein Unc-84 Homolog B (UNC84B)

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