Menu

Regulator of Nonsense Transcripts 1 (UPF1) Antibody

Catalogue No: abx001282
Price: £120.00
Reviews: 0 reviews
(0 reviews)

Click on the image to see the image legend

Regulator of Nonsense Transcripts 1 (UPF1) Antibody

Available Options

* Size:




UPF1 Antibody is a Rabbit Polyclonal antibody against UPF1. This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located only in the cytoplasm. When translation ends, it interacts with the protein that is a functional homolog of yeast Upf2p to trigger mRNA decapping. Use of multiple polyadenylation sites has been noted for this gene. Alternative splicing results in multiple transcript variants.

Target UPF1
Clonality Polyclonal
Reactivity Human, Mouse
Tested Applications WB, IF/ICC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen A synthetic peptide of human UPF1.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q92900 (UniProt, ExPASy)
UniProt Secondary AC O00239, O43343, Q86Z25, Q92842
UniProt Entry Name RENT1_HUMAN
Gene Symbol UPF1
GeneID 5976
String 9606.ENSP00000470142
Molecular Weight Calculated MW: 123 kDa, 124 kDa
Observed MW: 130 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Regulator of Nonsense Transcripts 1 (UPF1) Antibody

Write a review

Your Name
Your Email Address
PMID
DOI
Type
Your Review

Note: HTML is not translated!

Rating Bad Good


Tags:
(Click to show)