Ubiquitin Specific Peptidase 8 (USP8) Antibody

USP8 Antibody is a Rabbit Polyclonal antibody against USP8. This gene encodes a protein that belongs to the ubiquitin-specific processing protease family of proteins. The encoded protein is thought to regulate the morphology of the endosome by ubiquitination of proteins on this organelle and is involved in cargo sorting and membrane trafficking at the early endosome stage. This protein is required for the cell to enter the S phase of the cell cycle and also functions as a positive regulator in the Hedgehog signaling pathway in development. Pseudogenes of this gene are present on chromosomes 2 and 6. Alternate splicing results in multiple transcript variants.

Target	Ubiquitin Specific Peptidase 8 (USP8)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/1000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human USP8.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P40818 (UniProt, ExPASy)
UniProt Secondary AC	B4DKA8, Q2TB31, Q7Z3U2, Q86VA0, Q8IWI7
UniProt Entry Name	UBP8_HUMAN
Gene Symbol	USP8
GeneID	9101
NCBI Accession	NP_005145.3
KEGG	hsa:9101
String	9606.ENSP00000379721
Molecular Weight	Calculated MW: 128 kDa Observed MW: 140 kDa
Buffer	PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol.
Concentration	6.75 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Ubiquitin Specific Peptidase 8 (USP8)

Write a review

Your Name

Your Email Address

PMID

DOI

Your Review

Rating

Continue