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UV Radiation Resistance-Associated Gene Protein (UVRAG) Antibody
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Catalogue No: abx030358
Price:
US$326.25
(Size: 80 µl)
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UVRAG complements the ultraviolet sensitivity of xeroderma pigmentosum group C cells and encodes a protein with a C2 domain. The protein activates the Beclin1-PI (3) KC3 complex, promoting autophagy and suppressing the proliferation and tumorigenicity of human colon cancer cells. Chromosomal aberrations involving the UVAG gene are associated with left-right axis malformation and mutations in the gene have been associated with colon cancer.
Research Articles on UV Radiation Resistance-Associated Gene Protein (UVRAG)
| Target | UV Radiation Resistance-Associated Gene Protein (UVRAG) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 540-569 amino acids from the C-terminal region of human UVRAG. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q9P2Y5 (UniProt, ExPASy) |
| UniProt Secondary AC | B3KTC1, O00392 |
| UniProt Entry Name | UVRAG_HUMAN |
| NCBI Accession | NP_003360.2 |
| String | 9606.ENSP00000348455 |
| Molecular Weight | Calculated MW: 78.2 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |