VASP Antibody

Catalogue No: abx000578
Price: $308.00
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VASP Antibody

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VASP Antibody is a Rabbit Polyclonal antibody against VASP. Vasodilator-stimulated phosphoprotein (VASP) is a member of the Ena-VASP protein family. Ena-VASP family members contain an EHV1 N-terminal domain that binds proteins containing E/DFPPPPXD/E motifs and targets Ena-VASP proteins to focal adhesions. In the mid-region of the protein, family members have a proline-rich domain that binds SH3 and WW domain-containing proteins. Their C-terminal EVH2 domain mediates tetramerization and binds both G and F actin. VASP is associated with filamentous actin formation and likely plays a widespread role in cell adhesion and motility. VASP may also be involved in the intracellular signaling pathways that regulate integrin-extracellular matrix interactions. VASP is regulated by the cyclic nucleotide-dependent kinases PKA and PKG.

Target VASP
Reactivity Human, Mouse, Rat
Origin Human
Host Rabbit
Clonality Polyclonal
Tested Applications WB, IHC, IF/ICC, FCM, IP
Recommended dilutions WB: 1/500 - 1/2000, IHC: 1/50 - 1/200, IF/ICC: 1/50 - 1/100, FCM: 1/20 - 1/50. Optimal dilutions/concentrations should be determined by the end user.
Immunogen Recombinant fusion protein of human VASP.
Purification Affinity purified.
Isotype IgG
Conjugation Unconjugated
Storage Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.
Molecular Weight 40 kDa
Swiss Prot P50552
GeneID 7408
Gene Symbol VASP
Concentration > 1 mg/ml
Buffer PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Availability Shipped within 5-10 working days.
Note This product is for research use only.

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