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Vasodilator Stimulated Phosphoprotein Phospho-Ser239 (VASP pS239) Antibody
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Catalogue No: abx000239
Price:
US$232.00
(Size: 20 µl)
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VASP (pS239) Antibody is a Rabbit Polyclonal antibody against VASP (pS239). Vasodilator-stimulated phosphoprotein (VASP) is a member of the Ena-VASP protein family. Ena-VASP family members contain an EHV1 N-terminal domain that binds proteins containing E/DFPPPPXD/E motifs and targets Ena-VASP proteins to focal adhesions. In the mid-region of the protein, family members have a proline-rich domain that binds SH3 and WW domain-containing proteins. Their C-terminal EVH2 domain mediates tetramerization and binds both G and F actin. VASP is associated with filamentous actin formation and likely plays a widespread role in cell adhesion and motility. VASP may also be involved in the intracellular signaling pathways that regulate integrin-extracellular matrix interactions. VASP is regulated by the cyclic nucleotide-dependent kinases PKA and PKG.
Research Articles on Vasodilator Stimulated Phosphoprotein Phospho-Ser239 (VASP pS239)
| Target | Vasodilator Stimulated Phosphoprotein Phospho-Ser239 (VASP pS239) |
| Clonality | Polyclonal |
| Target Modification | Ser239 |
| Modification | Phosphorylation |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | ELISA: 1 µg/ml, WB: 1/500 - 1/1000, IHC-P: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Synthetic peptide corresponding to VASP pS239. The exact sequence is proprietary. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P50552 (UniProt, ExPASy) |
| UniProt Secondary AC | B2RBT9, Q6PIZ1, Q93035 |
| UniProt Entry Name | VASP_HUMAN |
| Gene Symbol | VASP |
| GeneID | 7408 |
| NCBI Accession | NP_003361.1 |
| KEGG | hsa:7408 |
| String | 9606.ENSP00000245932 |
| Molecular Weight | Calculated MW: 40 kDa Observed MW: 50 kDa |
| Buffer | PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |