Vascular Cell Adhesion Molecule 1 (VCAM1) Antibody
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Catalogue No: abx012173
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US$427.75
(Size: 100 µl)
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Datasheet SDS
This gene is a member of the Ig superfamily and encodes a cell surface sialoglycoprotein expressed by cytokine-activated endothelium. This type I membrane protein mediates leukocyte-endothelial cell adhesion and signal transduction, and may play a role in the development of artherosclerosis and rheumatoid arthritis. Two alternatively spliced transcripts encoding different isoforms have been described for this gene.Tissue specificity: Expressed on inflamed vascular endothelium, as well as on macrophage-like and dendritic cell types in both normal and inflamed tissue.INVITROGEN: CD106 is expressed on bone marrow stromal cells, myeloid cells, and endothelial cells.
Research Articles on Vascular Cell Adhesion Molecule 1 (VCAM1)
| Target | Vascular Cell Adhesion Molecule 1 (VCAM1) |
| Research Area | Cellular Differentiation and Adhesion, Tumor Immunity, Infection Immunity, Neuroscience, Cancer |
| Clonality | Monoclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC |
| Host | Mouse |
| Recommended dilutions | ELISA: 1/10000, WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Purified recombinant fragment of human VCAM1 expressed in E. coli. |
| Isotype | IgG1 |
| Form | Liquid |
| Purification | Unpurified ascites. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P19320 (UniProt, ExPASy) |
| UniProt Secondary AC | A8K6R7, B4DKS4, E9PDD1, Q6NUP8 |
| UniProt Entry Name | VCAM1_HUMAN |
| Gene Symbol | VCAM1 |
| GeneID | 7412 |
| OMIM | 192225 |
| HGNC | 12663 |
| KEGG | hsa:7412 |
| Ensembl | ENSG00000162692 |
| String | 9606.ENSP00000294728 |
| Molecular Weight | 81 kDa |
| Buffer | Ascitic fluid containing 0.03% sodium azide. |
| Concentration | Not determined. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |