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Vacuolar Protein Sorting-Associated Protein 4A (VPS4A) Antibody
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Catalogue No: abx005363
Price:
US$203.00
(Size: 20 µl)
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VPS4A Antibody is a Rabbit Polyclonal antibody against VPS4A. The protein encoded by this gene is a member of the AAA protein family (ATPases associated with diverse cellular activities), and is the homolog of the yeast Vps4 protein. In humans, two paralogs of the yeast protein have been identified. The former share a high degree of aa sequence similarity with each other, and also with yeast Vps4 and mouse Skd1 proteins. The mouse Skd1 (suppressor of K+ transport defect 1) has been shown to be really an yeast Vps4 ortholog. Functional studies indicate that both human paralogs associate with the endosomal compartments, and are involved in intracellular protein trafficking, similar to Vps4 protein in yeast. The gene encoding this paralog has been mapped to chromosome 16; the gene for the other resides on chromosome 18.
Research Articles on Vacuolar Protein Sorting-Associated Protein 4A (VPS4A)
| Target | Vacuolar Protein Sorting-Associated Protein 4A (VPS4A) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB, IHC, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000, IHC-P: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | A synthetic peptide corresponding to a sequence within amino acids 1-120 of human VPS4A. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q9UN37 (UniProt, ExPASy) |
| UniProt Secondary AC | B2RCB7, Q8TF07, Q9UI03, Q9Y582 |
| UniProt Entry Name | VPS4A_HUMAN |
| Gene Symbol | VPS4A |
| GeneID | 27183 |
| NCBI Accession | NP_037377.1 |
| String | 9606.ENSP00000254950 |
| Molecular Weight | Calculated MW: 49 kDa Observed MW: 49 kDa |
| Buffer | PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |
