Vacuolar Protein Sorting-Associated Protein 4B (VPS4B) Antibody
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Catalogue No: abx027624
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US$326.25
(Size: 80 µl)
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Datasheet SDS
The protein encoded by this gene is a member of the AAA protein family (ATPases associated with diverse cellular activities), and is the homolog of the yeast Vps4 protein. In humans, two paralogs of the yeast protein have been identified. The former share a high degree of aa sequence similarity with each other, and also with yeast Vps4 and mouse Skd1 proteins. Mouse Skd1 (suppressor of K+ transport defect 1) has been shown to be a yeast Vps4 ortholog. Functional studies indicate that both human paralogs associate with the endosomal compartments, and are involved in intracellular protein trafficking, similar to Vps4 protein in yeast. The gene encoding this paralog has been mapped to chromosome 18; the gene for the other resides on chromosome 16. [provided by RefSeq].
Research Articles on Vacuolar Protein Sorting-Associated Protein 4B (VPS4B)
| Target | Vacuolar Protein Sorting-Associated Protein 4B (VPS4B) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 304-332 amino acids from the C-terminal region of human VPS4B. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | O75351 (UniProt, ExPASy) |
| UniProt Secondary AC | Q69HW4, Q9GZS7 |
| UniProt Entry Name | VPS4B_HUMAN |
| Gene Symbol | VPS4B |
| GeneID | 9525 |
| OMIM | 609983 |
| HGNC | 10895 |
| KEGG | hsa:9525 |
| Ensembl | ENSG00000119541 |
| String | 9606.ENSP00000238497 |
| Molecular Weight | Calculated MW: 49.3 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |