WD Repeat-Containing Protein 4 (WDR4) Antibody

This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This gene is excluded as a candidate for a form of nonsyndromic deafness (DFNB10), but is still a candidate for other disorders mapped to 21q22.3 as well as for the development of Down syndrome phenotypes. Two transcript variants encoding the same protein have been found for this gene.

Target	WD Repeat-Containing Protein 4 (WDR4)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB
Host	Rabbit
Recommended dilutions	WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 146-173 amino acids from the Central region of human WDR4.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P57081 (UniProt, ExPASy)
UniProt Secondary AC	A8KA58, B2RCA3, B4DNQ7, D3DSK3, Q9BVM5, Q9HCR3
UniProt Entry Name	WDR4_HUMAN
KEGG	hsa:10785
String	9606.ENSP00000381266
Molecular Weight	Calculated MW: 45.5 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Mouse and Cow WDR4.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on WD Repeat-Containing Protein 4 (WDR4)

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